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KMID : 0381919980280020127
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Korean Journal of Microscopy
1998 Volume.28 No. 2 p.127 ~ p.137
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Morphologic Study on the Changes of Skin Structure of Hairless Mouse by Ultraviolet Irradiation
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Song Sun-Young
Yoon Jung-Sik
Cheong Min-Ju
Chung Kyung-A
Roh Young-Bok
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Abstract
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This study was observed of the skin that changed after irradiation of the ultraviolet A. All the mouse were hairless which the weight are about 25g and the ages $6\sim8$ weeks old. The mouse were divided into six groups; control, irradiated for 6 hours, 3 days, 7 days, 14 days, 21 days and 28 days. Each group was irradiated with ultraviolet that is $320nm\sim366nm$ of wavelengths. After irradiated, the skin was observed with the electron microscope and the light microscope. The results are as follow: 1) Light microscopy With following irradiation, the epidermis was not changed to most groups but at the 28 days group was thickened and deposit the melanocyte. The elastic fibers within the epidermis were thickened and twisted with following irradiation. 2) Eelectron microscopy The elastic fibers were slightly clumped at 6 hours group, mildly increased and partly aggregated in the 3 days group, branched and tangled at 7 days group, irregulated and electron density at 14 days group, sightly thickened and twisted at 21 days group, and randomly arranged, shortened, twisted, and electron density at 28 days group.
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KEYWORD
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Ultraviolet A, Elastic fiber, Hairless mouse, TEM
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